加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

Beclin 1/BECN1抗体图片
产品货号:
Z11540
中文名称:
Beclin 1/BECN1抗体
英文名称:
Anti-Beclin 1/BECN1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Beclin 1/BECN1 Antibody
指标别名ATG6;Beclin 1;beclin 1;autophagy related;beclin1;BECN1;GT197;Protein GT197;VPS30;Beclin-1
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF,FCM
基因名称BECN1
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Beclin 1 recombinant protein (Position:M1-S354).Human Beclin 1 shares 97% amino acid (aa) sequence identity with both mouse and rat Beclin 1.
实际分子量52~60KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Beclin-1,also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene.Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K),also named Vps34,are required for the initiation of the formation of the autophagosome in autophagy.This gene participates in the regulation of autophagy and has an important role in development,tumorigenesis,and neurodegeneration.Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagywhich in turn results in increased neuronal cell death.It has been found that beclin-1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30,and in human MCF7 breast carcinoma cells.
Uniprot IDQ14457
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称beclin 1,autophagy related
蛋白名全称Beclin-1
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:Beclin 1/BECN1抗体Beclin 1抗体BECN1多抗Anti-Beclin 1/BECN1 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3